linezolid, Zyvox

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: linezolid

BRAND NAME: Zyvox

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Linezolid is used for treating pneumonia, complicated and uncomplicated skin and skin structure infections, and vancomycin-resistant Enterococcus faecium infections.

SIDE EFFECTS:

Common side effects of linezolid include:

Other possible side effects of linezolid include:

Possible serious side effects of linezolid include:

Cases of hypoglycemia have been reported during treatment with linezolid in patients with diabetes who are receiving insulin or oral hypoglycemic medications.

People who are taking drugs that may increase blood pressure should not receive linezolid or should be monitored closely for potential increases in blood pressure.

Linezolid should not be used for the treatment of catheter-related bloodstream infections or catheter-site infections since more people in the linezolid treated groups died in an investigational study of patients with these catheter-related bloodstream infections.

Like other antibiotics, linezolid may cause Clostridium difficile associated diarrhea or colitis.

Linezolid may suppress the bone marrow. Therefore, complete blood cell counts should be obtained weekly and discontinuation of treatment should be considered in patients who develop or have worsening bone marrow suppression.

Peripheral and optic neuropathy may occur, most often in patients treated for longer than 28 days. Patients who experience visual impairment should be evaluated immediately.

To reduce the risk of serotonin syndrome patients taking serotonergic antidepressants should only receive linezolid if other options are not available.

Medically Reviewed by a Doctor on 1/21/2016

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