lincomycin (hydrochloride; Lincocin) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Safe and effective use of lincomycin is not established for infants of age less than 1 month old.

DRUG INTERACTIONS: Lincomycin should be used with caution with neuromuscular blocking medications such as atracurium (Tracrium), pancuronium (Pavulon), rocuronium (Zemuron), succinylcholine (Anectine), and vecuronium. Lincomycin may increase the effects of neuromuscular blockage and lead to respiratory depression.

PREGNANCY: There are no adequate studies done on lincomycin to determine safe and effective use in pregnant women.

NURSING MOTHERS: Lincomycin may be excreted in small amounts in breast milk. Therefore, caution should be exercised before using it in nursing mothers. To avoid the potential harm to nursing infants, a decision should be made whether to discontinue drug or discontinue nursing before using in nursing mothers.

SIDE EFFECTS: Side effects of lincomycin are nausea, vomiting, diarrhea, abdominal pain, rash, and itching.

Like other antibiotics lincomycin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after treatment with lincomycin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.

REFERENCE: FDA Prescribing Information.


Medically Reviewed by a Doctor on 6/27/2014


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