lincomycin (hydrochloride; Lincocin)

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GENERIC NAME: Lincomycin hydrochloride

BRAND NAME: Lincocin

DRUG CLASS AND MECHANISM: Lincomycin is an injectable man-made antibiotic. Lincomycin kills bacteria by interfering with the ability of bacteria to produce important proteins necessary for them to survive. Lincomycin is effective against many types of bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Propionibacterium acnes, and others. The FDA approved lincomycin in December 1964.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Lincomycin is available in 300mg/ml sterile, injection form. It is available in 2 ml and 10 ml vials used for intramuscular and intravenous administration.

STORAGE: Store lincomycin at room temperature between 20 C to 25 C (68 F to 77 F).

PRESCRIBED FOR: Lincomycin is used for treating serious bacterial infections caused by susceptible strains of streptococci, pneumococci, and staphylococci. Use of lincomycin is reserved for penicillin-allergic patients or when penicillin-based treatment is not appropriate. This antibiotic should only be used to treat serious infections because of rare but sometimes fatal intestinal problems have occurred (pseudomembranous colitis).

DOSING:

Intramuscular

  • Adults: Inject 600 mg every 24 hours. May use 600 mg every 12 hours or more often for severe infections, if needed.
  • Pediatric patients of 1 month of age and older: Inject 10 mg/kg every 24 hours. May use 10 mg/kg every 12 hours or more often for severe infections, if needed.

IV

  • Adults: Administer 600 mg to 1000 mg every 8 to 12 hours. May increase doses for more severe infections, but the maximum daily dose of 8000 mg of lincomycin is recommended; higher rates and doses have been associated with severe cardiopulmonary reactions.
  • Pediatric patients of 1 month of age and older: Administer 10 to 20 mg/kg/day in divided doses over 8 to 12 hours.
Medically Reviewed by a Doctor on 6/27/2014



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