linagliptin, Tradjenta

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Type 2 Diabetes Warning Signs

SIDE EFFECTS AND PRECAUTIONS: The most common side effects of linagliptin are:

Hypoglycemia may occur when linagliptin is combined with insulin or a sulfonylurea-type drug. and also may occur.

GENERIC AVAILABLE: No

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 5 mg

STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F)

DOSING: Linagliptin may be taken with or without food. The recommended dose is 5 mg once daily.

DRUG INTERACTIONS: Rifampin decreases the blood concentration of linagliptin by stimulating break down of linagliptin by CYP3A4 liver enzymes. Other drugs that increase activity CYP3A4 may also reduce the blood concentration of linagliptin.

PREGNANCY: There are no adequate studies of linagliptin in pregnant women.

NURSING MOTHERS: It is unknown whether linagliptin is secreted in human breast milk.

Medically reviewed by Eni Williams, PharmD

REFERENCE: FDA prescribing information.

Medically Reviewed by a Doctor on 4/3/2015

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