SIDE EFFECTS AND PRECAUTIONS: The most common side effects of linagliptin are:
Hypoglycemia may occur when linagliptin is combined with insulin or a sulfonylurea-type drug. and also may occur.
GENERIC AVAILABLE: No
PREPARATIONS: Tablets: 5 mg
STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F)
DOSING: Linagliptin may be taken with or without food. The recommended dose is 5 mg once daily.
DRUG INTERACTIONS: Rifampin decreases the blood concentration of linagliptin by stimulating break down of linagliptin by CYP3A4 liver enzymes. Other drugs that increase activity CYP3A4 may also reduce the blood concentration of linagliptin.
PREGNANCY: There are no adequate studies of linagliptin in pregnant women.
NURSING MOTHERS: It is unknown whether linagliptin is secreted in human breast milk.
Medically reviewed by Eni Williams, PharmD
REFERENCE: FDA prescribing information.
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