Tradjenta (linagliptin)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What brand names are available for linagliptin?


Is linagliptin available as a generic drug?


Do I need a prescription for linagliptin?


What are the uses for linagliptin?

  • Tradjenta is combined with diet and exercise to improve blood glucose levels in patients with type 2 diabetes.
  • It should not be used for treating type 1 diabetes or diabetic ketoacidosis because it would not be effective in these conditions.
  • Tradjenta has not been studied in patients with a history of pancreatitis. It is unknown whether Tradjenta increases the risk for the development of pancreatitis in patients who have a history of pancreatitis.

What are the side effects of linagliptin?

The most common side effects of Tradjenta are:

Hypoglycemia may occur when Tradjenta is combined with insulin or a sulfonylurea-type drug.

Possible serious side effects include:

  • Pancreatitis
  • Severe joint pain
  • Severe allergic reactions (anaphalaxis)

Quick GuideDiabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating

Diabetes Diet: Healthy Meal Plans for Diabetes-Friendly Eating

What is the dosage for linagliptin?

Tradjenta may be taken with or without food. The recommended dose is 5 mg once daily.

Which drugs or supplements interact with linagliptin?

  • Rifampin decreases the blood concentration of Tradjenta by stimulating break down of Tradjenta by CYP3A4 liver enzymes. Other drugs that increase activity CYP3A4 may also reduce the blood concentration of Tradjenta.

Is linagliptin safe to take if I'm pregnant or breastfeeding?

  • There are no adequate studies of Tradjenta in pregnant women.
  • It is unknown whether Tradjenta is secreted in human breast milk.

What else should I know about linagliptin?

What preparations of linagliptin are available?

Tablets: 5 mg

How should I keep linagliptin stored?

Tablets should be stored at room temperature, 15-30 C (59-86 F)

REFERENCE: FDA prescribing information.

Last Editorial Review: 9/14/2016

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See more info: linagliptin on RxList
Reviewed on 9/14/2016
REFERENCE: FDA prescribing information.

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