GENERIC NAME: lidocaine and prilocaine
BRAND NAME: DermacinRx, Prizopak, EMLA, Leva Set, Lidopril, Livixil Pak, LP Lite Pak, Oraqix, Relador Pak, Venipuncture CPI
GENERIC AVAILABLE: Yes
USES: Lidocaine and prilocaine cream is commonly used as a local anesthetic on normal intact skin and genital mucous areas, before minor procedures.
SIDE EFFECTS: Common side effects of lidocaine and prilocaine are:
Other rare side effects include:
- central nervous system depression,
- hypersensitivity reactions, and
- hypotension (low blood pressure).
PREPARATIONS: Lidocaine and prilocaine is a combination cream, containing 2.5% of each component. Lidocaine and prilocaine is available in 5 gram and 30 gram tubes.
DRUG INTERACTIONS: Lidocaine and prilocaine should not be used together with anti-arrhythmic drugs such as tocainide (Tonocard) and mexiletine (Mexitil), due to additive effects on heart rate and rhythm.
Prilocaine may contribute to formation of methemoglobin in patients treated with other drugs known to cause methemoglobinemia.
Lidocaine and prilocaine should be used with caution with anti-arrhythmic drugs like amiodarone (Cordarone), sotalol (Betapace), bretylium, and dofetilide (Tikosyn) because of increased risk developing abnormal heart rate and rhythm.
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