lidocaine HCl injection, Xylocaine

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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People allergic to anesthetics similar to lidocaine should not use lidocaine.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Injectable Solution: 0.5%, 1%, 1.5%, 2%, 4%, and 5%; 200, 400 and 800 mg/100 mL

STORAGE: All solutions should be stored at room temperature, 25 C (77 F) and protected from light.

DOSING: Dosing varies considerably depending on the use. Total recommended doses range from 20 mg to 300 mg.

DRUG INTERACTIONS: Administering lidocaine solutions containing epinephrine or norepinephrine (which are added to prolong the action of the lidocaine) to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe and prolonged high blood pressure. Such combinations should be avoided. A similar reaction may occur with drugs used to increase blood pressure (vasopressors).

PREGNANCY: Lidocaine has not been adequately studied in pregnant women. Studies in animals have not shown evidence of harm to the fetus.

NURSING MOTHERS: It is not known whether lidocaine is excreted in breast milk.

Medically reviewed by Eni Williams, PharmD

REFERENCE: FDA prescribing information.

Medically Reviewed by a Doctor on 12/31/2014

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