lidocaine injection (Xylocaine)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jerry R. Balentine, DO, FACEP
    Jerry R. Balentine, DO, FACEP

    Jerry R. Balentine, DO, FACEP

    Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.

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PREGNANCY: There are no adequate studies of use in pregnant women. Available evidence does not suggest harm to the fetus. Lidocaine crosses the placenta and does enter the fetal blood stream so close monitoring of the heart is recommended.

NURSING MOTHERS: Lidocaine is excreted in breast milk so it should be used cautiously by nursing mothers. The amount absorbed by the infant is not expected to be significant.

SIDE EFFECTS: Side effects vary by dose and site of administration. The most common adverse reactions include low heart rate, low blood pressure, backache, dizziness, lightheadedness, and numbness. Additional side effects include shivering, tingling, sedation, blurry vision, confusion, nervousness, and euphoria. Rare, but serious side effects include cardiac arrest, methemoglobinemia, breakdown of cartilage, seizure, and loss of consciousness.

REFERENCE: FDA Prescribing Information.

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