levodopa-carbidopa, Sinemet, Sinemet CR, Parcopa

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GENERIC NAME: carbidopa-levodopa

BRAND NAME: Sinemet, Sinemet CR, Parcopa

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

USES: Carbidopa-levodopa is used for the management of Parkinson's disease.

SIDE EFFECTS: Most patients receiving carbidopa-levodopa experience side effects, but these usually are reversible.

Gastrointestinal side effects are common in patients receiving carbidopa-levodopa and these include:

Patients may experience dizziness upon standing up, associated with a drop in blood pressure. Fortunately, the body develops tolerance to this side effect within a few months.

Other important side effects of carbidopa-levodopa therapy include:

 Occasional involuntary movements are the most common of the serious side effects of carbidopa-levodopa therapy, and these are:

  • muscle twitching,
  • dizziness,
  • muscle jerks during sleep,
  • hand tremor,
  • chewing,
  • gnawing,
  • twisting,
  • tongue or
  • mouth movements,
  • head bobbing, or
  • movements of the feet, hands, or shoulder which may respond to a reduction in the dose.

Infrequently, patients may develop a drop in white blood cell count during carbidopa-levodopa therapy. This is a significant reason to temporarily, if not permanently, stop treatment.

Medically Reviewed by a Doctor on 6/30/2016

Quick GuideParkinson's Disease: Symptoms, Causes, Stages, and Treatment

Parkinson's Disease: Symptoms, Causes, Stages, and Treatment
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