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leuprolide monthly (3.75 mg) - injection, Lupron Depot (cont.)

HOW TO USE: This medication is given as an injection into a muscle (intramuscularly), usually once a month by a health care professional or as directed by your doctor. This product slowly releases the medication into your blood over a 1-month period.In women, the length of treatment is based on your medical condition, response to therapy, and the condition of your bones since leuprolide may weaken bones. Consult your doctor for details. See also Precautions section.In children, the dosage is based on weight and response to therapy. The doctor should consider stopping treatment before age 11 for girls and age 12 for boys. Consult your doctor for details.If you are directed to inject this medication yourself, learn all preparation and usage instructions in the product package. Learn how to store and discard needles and medical supplies safely. If any of the information is unclear, consult your doctor or pharmacist.Change the location of the injection site each time to avoid problem areas under the skin.Use this medication regularly to get the most benefit from it. To help you remember, mark your calendar to keep track of when to receive the next dose.Inform your doctor if your condition persists or worsens. In women, improvement in symptoms is usually seen in 3-6 months.

SIDE EFFECTS: Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal discomfort/dryness, abnormal vaginal bleeding (in girls), swelling of the ankles/feet, dizziness, or mild burning/pain/bruising at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.When this medication is used regularly, it is expected that the menstrual period will stop (or decrease to light bleeding/spotting). Menstrual periods usually return within 2 months after treatment is stopped. Tell your doctor promptly if regular periods continue during treatment with leuprolide.During the first few weeks of treatment, your hormone levels will actually increase before they decrease. This is a normal response by your body to this drug. This may result in a temporary worsening of your symptoms for a few weeks.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., new or worsening depression, thoughts of suicide, mood swings, memory problems, aggression in children), bone pain (in adults), easily broken bones (in adults).Rarely, a very serious problem with your pituitary gland (pituitary apoplexy) may occur, usually in the first hour to 2 weeks after your first injection. Seek immediate medical attention if any of these very serious side effects occur: sudden severe headache, sudden severe mental/mood changes (e.g., severe confusion, difficulty concentrating), vision changes, severe vomiting, fainting.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.



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