leuprolide, (Lupron, Lupron Depot, Lupron Depot-Ped, Eligard) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Testosterone promotes the growth of prostate cancer. Therefore, leuprolide is used in treating prostate cancer to slow the growth of the cancer. In children with central precocious puberty (puberty caused at an early age because of too much LH and FSH) leuprolide, by suppressing LH and FSH, reduces the levels of estrogen and testosterone and allows for more normal timing of puberty. Estrogens promote the growth of fibroids (benign tumors of the uterus) and areas of endometriosis (abnormal uterine tissue that exists outside of the uterus). Leuprolide is used to reduce the production of estrogen and treat both fibroids and endometriosis. The FDA approved leuprolide in April 1985.
PRESCRIBED FOR: Leuprolide is used for the treatment of advanced prostatic cancer, endometriosis, fibroids, and central precocious puberty.
SIDE EFFECTS: The most common side effects of leuprolide are:
Other important side effects of leuprolide include:
GENERIC AVAILABLE: Yes.
PREPARATIONS: Leuprolide injection: 5 mg/ml and 3.75 mg . Lupron Depot microspheres for injection: 3.75, 7.5, 15, 11.25, 22.5, 30, and 45 mg/vial.
STORAGE: Leuprolide should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).
DOSING: Leuprolide is injected under the skin (subcutaneously). Lupron Depot is injected into muscle (intramuscularly).
Medically Reviewed by a Doctor on 4/3/2015
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