- What is letrozole, and how does it work (mechanism of action)?
- What brand names are available for letrozole?
- Is letrozole available as a generic drug?
- Do I need a prescription for letrozole?
- What are the side effects of letrozole?
- What is the dosage for letrozole?
- Which drugs or supplements interact with letrozole?
- Is letrozole safe to take if I'm pregnant or breastfeeding?
- What else should I know about letrozole?
What is letrozole, and how does it work (mechanism of action)?
Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands (aromatase) that produces the estrogens, estradiol and estrone. Letrozole was approved by the FDA in 1997.
What brand names are available for letrozole?
Is letrozole available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for letrozole?
What are the side effects of letrozole?
The most common side effects with letrozole are:
Cholesterol levels may increase during letrozole therapy. Cholesterol levels should be monitored and some patients may require treatment for high cholesterol levels. Letrozole decreases bone mineral density, increasing the risk of osteoporosis and fractures.
Quick GuideBreast Cancer Diagnosis and Treatment
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