Leptospirosis (cont.)

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Is it possible to prevent leptospirosis?

A vaccine is not available in the U.S.; high-risk workers in some European and Asian countries may have access to a vaccine. Unfortunately, the vaccines are serovar specific (bacterial-strain specific) and thus do not offer widespread protection. Some vaccines are available for animals but these, like the human vaccines, are only effective against a narrow range of serovars. In addition, side effects of the vaccine can cause painful swelling. Some individuals who may have high short-time risk (for example, military personnel) may take doxycycline (200 mg/week) to have about a 95% chance of preventing infection. This preventive treatment is not recommended for long terms of exposure.

Avoiding contact with animal excrement, good hygiene, and avoiding contaminated water and soil are other ways to reduce the chance of getting leptospirosis.

Medically reviewed by Robert Cox, MD; American Board of Internal Medicine with subspecialty in Infectious Disease


Green-McKenzie, Judith. "Leptospirosis in Emergency Medicine." July 9, 2012. <http://emedicine.medscape.com/article/788751-overview>.

United States. Centers for Disease Control and Prevention. "Leptospirosis." June 24, 2013. <http://www.cdc.gov/leptospirosis/index.html>.

Medically Reviewed by a Doctor on 11/11/2015