Leprosy Glossary of Terms
The following are health and medical definitions of terms that appear in the Leprosy article. Adenopathy: Large or "swollen" lymph nodes. Synonymous with lymphadenopathy.
Alopecia: Baldness. There are many types of alopecia, each with a different cause. Alopecia may be localized to the front and top of the head as in common male pattern baldness. It may be patchy as in a condition called alopecia areata. Or it can involve the entire head as in alopecia capitis totalis. The word "alopecia" comes from the Greek "alopex" for "fox." Foxes are less furry when afflicted with a skin disease (the "mange") which causes them to lose their hair. When a fancier word for "baldness" was sought, the mangy fox supplied it -- "alopecia" or, if you wish, "fox-mange" -- not a very positive image to associate with baldness!
Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
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Anesthesia: Loss of feeling or awareness. A general anesthetic puts the person to sleep. A local anesthetic causes loss of feeling in a part of the body such as a tooth or an area of skin without affecting consciousness. Regional anesthesia numbs a larger part of the body such as a leg or arm, also without affecting consciousness. The term "conduction anesthesia" encompasses both local and regional anesthetic techniques. Many surgical procedures can be done with conduction anesthesia without significant pain. In many situations, such as a C-section, conduction anesthesia is safer and therefore preferable to general anesthesia. However, there are also many types of surgery in which general anesthesia is clearly appropriate.
Anesthetic: A substance that causes lack of feeling or awareness. A local anesthetic causes loss of feeling in a part of the body. A general anesthetic puts the person to sleep.
Antibiotic: A drug used to treat infections caused by bacteria and other microorganisms. Originally, an antibiotic was a substance produced by one microorganism that selectively inhibits the growth of another. Synthetic antibiotics, usually chemically related to natural antibiotics, have since been produced that accomplish comparable tasks.
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Aseptic: The absence of microorganisms. By contrast, something that just discourages the growth of microorganisms is antiseptic.
Aseptic necrosis: Condition in which poor blood supply to an area of bone leads to bone death. Also called avascular necrosis and osteonecrosis.
Bacillus: A large family of bacteria that have a rod-like shape. They include the bacteria that cause food to spoil, and also those responsible for some types of diseases. Helpful members of the bacillus family are used to make antibiotics, or colonize the human intestinal tract and aid with digestion.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterium: The singular of bacteria.
Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bumps: The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.
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CBC: A commonly used abbreviation in medicine that stands for complete blood count , a set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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CDC: The Centers for Disease Control and Prevention , the US agency charged with tracking and investigating public health trends. The stated mission of the CDC is "To promote health and quality of life by preventing and controlling disease, injury, and disability." The CDC is a part of the U.S. Public Health Services (PHS) under the Department of Health and Human Services (HHS).
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Creatinine: A chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Genetic: Having to do with genes and genetic information.
Hair loss : Hair loss is the thinning of hair on the scalp. The medical term for hair loss is alopecia . Alopecia can be temporary or permanent. The most common form of hair loss occurs gradually and is referred to as "androgenetic alopecia," meaning that a combination of hormones (androgens are male hormones) and heredity ( genetics ) is needed to develop the condition. Other types of hair loss include alopecia areata (patches of baldness that usually grow back), telogen effluvium (rapid shedding after childbirth, fever , or sudden weight loss); and traction alopecia (thinning from tight braids or ponytails).
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Hansen's disease: See: Hansen disease.
Hypopigmented: Underpigmented.
Immune: Protected against infection. The Latin immunis means free, exempt.
Immune response: Any reaction by the immune system.
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Intracellular: Within a cell. In contrast to extracellular, meaning outside a cell.
Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Leper: 1. Someone with leprosy (Hansen disease). The term leper is now in disfavor. 2. By extension, a pariah. A person who is avoided or shunned by society.
From the French lepre, from the Greek lepros meaning scaly, referring to the scales that form on the skin in some cases of leprosy.
Leprosy: See: Hansen disease.
Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
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Limb: The arm or leg.
Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.
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Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.
Lymphocytes: A small white blood cell ( leukocyte ) that plays a large role in defending the body against disease.
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Macules: Small circumscribed changes in the color of skin that are neither raised (elevated) nor depressed. Macules are never large. They are basically little spots or blemishes in the skin. They are entirely flat and can only be appreciated by visual inspection; they cannot be seen from the side.
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Malaria : An infectious disease caused by protozoan parasites from the Plasmodium family that can be transmitted by the sting of the Anopheles mosquito or by a contaminated needle or transfusion. Falciparum malaria is the most deadly type.
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Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
Microscopic: So small it cannot be seen without the aid of microscope. As opposed to macroscopic (large enough to be seen with naked eye). A tiny tumor is microscopic while a big tumor is macroscopic.
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Minocin: Brand name for minocycline.
Minocycline: A tetracycline antibiotic used to treat many different bacteria in urinary tract infections, acne , gonorrhea , and chlamydia , and other injections. The brand names for minocycline include Dynacin, Minocin, and Vectrin.
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Mycobacteria: Plural of mycobacterium.
Mycobacterium: A large family of bacteria that have unusually waxy cell walls that are resistant to digestion.
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Mycobacterium leprae: The bacillus responsible for leprosy (Hansen disease). Mycobacterium leprae is an obligate parasite that has to live within cells. There it is able to withstand the onslaught of enzymes and other forces by virtue of possessing a peculiarly resistant waxy coat and thanks also to its association with lowered cellular immunity. See also: Hansen disease.
Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.
Necrosis: The death of living cells or tissues. Necrosis can be due, for example, to ischemia (lack of blood flow). From the Greek "nekros" (dead body).
Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.
Neural: Having to do with nerve cells.
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NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers.
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Nose: The external midline projection from the face.
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Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Papules: Small solid rounded bumps rising from the skin that are each usually less than 1 centimeter in diameter (less than 3/8 inch across).
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Peripheral: Situated away from the center, as opposed to centrally located.
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Peripheral nervous system (PNS): That portion of the nervous system that is outside the brain and spinal cord.
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Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
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Regress: To return or go back, particularly to return to a pattern of behavior or level of skill characteristic of a younger age. For example, if a three-year-old child begins to regress by losing the ability to control his bowels or speak, that is a cause for medical concern. In reference to a disease, to "regress," means tending to worsen.
Residual: Something left behind. With residual disease, the disease has not been eradicated.
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Resistance: Opposition to something, or the ability to withstand it. For example, some forms of staphylococcus are resistant to treatment with antibiotics.
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Resolution: In genetics , resolution refers to the degree of molecular detail on a physical map of DNA , ranging from low to high.
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Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Testicles: The testicles (also called testes or gonads) are the male sex glands. They are located behind the penis in a pouch of skin called the scrotum. The testicles produce and store sperm, and they are also the body's main source of male hormones (testosterone). These hormones control the development of the reproductive organs and other male characteristics, such as body and facial hair, low voice, and wide shoulders.
Therapy: The treatment of disease .
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Tuberculosis : A highly contagious infection caused by the bacterium called Mycobacterium tuberculosis. Abbreviated TB. Tubercles (tiny lumps) are a characteristic finding in TB. Diagnosis may be made by skin test, which if positive should will be followed by a chest X-ray to determine the status (active or dormant) of the infection. Tuberculosis is more common in people with immune system problems, such as AIDS, than in the general population. Treatment of active tuberculosis is mandatory by law in the US, and should be available at no cost to the patient through the public health system. It involves a course of antibiotics and vitamins that lasts about six months. It is important to finish the entire treatment, both to prevent reoccurrence and to prevent the development of antibiotic-resistant tuberculosis. Most patients with tuberculosis do not need to be quarantined, but it is sometimes necessary.
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- Liver Blood Tests - Learn about liver blood tests used to detect liver damage disease such as fatty liver, cirrhosis, hepatitis, Tylenol liver damage, and more. This includes measuring the aminotransferases enzymes (AST and ALT levels)
- Foot Pain - Read about causes, symptoms, diagnosis and treatment of foot pain. Pain in the feet may be caused by poorly fitting shoes, injuries, or diseases such as diabetes and gout.
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