Laxatives For Constipation (cont.)

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Lubricant laxatives

Mineral oil (liquid petrolatum) coats and softens stool. Like stool softeners, mineral oil is used by patients who need to avoid straining (for example, after hernia repair, hemorrhoid surgery, heart attacks, and childbirth).

Precautions for using lubricant laxatives

  • Mineral oil should be avoided in individuals taking blood thinners, such as warfarin (Coumadin). Mineral oil decreases the absorption of vitamin K (important in forming clotting factors in the blood) from the intestines. The decreased absorption of vitamin K in patients taking warfarin can potentially lead to "over-thinning" of the blood and increasing the risk of excessive bleeding.
  • Mineral oil should not be taken during pregnancy since it may inhibit vitamin absorption and decrease the availability of vitamin K to the fetus.
  • Mineral oil can cause pneumonia if it leaks into the lungs. Leakage of secretions and other contents from the mouth and the esophagus into the lungs is called aspiration. Certain individuals (for example, the very young, the elderly, stroke victims, and those with swallowing difficulties) are prone to aspirate, especially while lying down. Therefore, mineral oil should not be given at bedtime or to individuals who are prone to aspirate.
  • Mineral oil should only be used for short periods of time. A significant absorption of mineral oil into the body can occur if used repeatedly over prolonged periods.
Reviewed by Jay W. Marks, MD on 9/14/2011

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