latanoprost, Xalatan

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Discoloration of the iris begins slowly. It is caused by an increase in the amount of brown pigment in the iris and may be permanent. Other side effects which have been reported less frequently include:

  • dryness of the eyes,
  • increased tearing,
  • eye pain,
  • and other eye-related discomfort.

elash changes such as increased length, thickness, and number of lashes may occur. Conjunctivitis, double vision, and eye discharge are rare side effects of latanoprost.


GENERIC AVAILABLE: Yes PREPARATIONS: Ophthalmic solution: 50 g/ml, 2.5ml.

STORAGE: Latanoprost should be kept at room temperature, 15 C to 30 C (59 F to 86 F) and protected for direct light.

DOSING: The usual dose is one drop into the affected eye or eyes once daily in the evening. The hands should be washed before each use of latanoprost or any eye medication. Contact lenses should be removed. The head is tilted back and the lower eyelid is pulled down with the index finger to form a pouch. (It is important not to touch the tip of the dropper to the eye or the eyelid so that bacteria are not introduced into the bottle.) The bottle is squeezed slightly to allow the prescribed number of drops into the pouch. The eye is closed gently for 2 to 3 minutes without blinking.

DRUG INTERACTIONS: Mixing eye drops containing thimerosal with latanoprost may cause precipitation of the chemicals within the drops. Therefore, thimerosal eye drops and latanoprost should be administered at least 5 minutes apart. Combining latanoprost with other prostaglandin eye drops may reduce the effect of latanoprost and may even increase intraocular pressure.

PREGNANCY: There are no adequate studies in pregnant women. Physicians should use latanoprost during pregnancy only if its benefits are felt to outweigh the potential risks to the fetus.

NURSING MOTHERS: It is not known if latanoprost is secreted into breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 4/3/2015
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