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lansoprazole/amoxicillin/clarithromycin - oral, Prevpac (cont.)

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: "blood thinners" (such as warfarin), colchicine, digoxin, ergot alkaloids (such as dihydroergotamine, ergotamine), methotrexate, HIV NNRTIs (such as delavirdine, efavirenz, etravirine, nevirapine), probenecid, some HIV protease inhibitors (such as atazanavir, darunavir, lopinavir, ritonavir, tipranavir), rifamycins (such as rifabutin), live bacterial vaccines.Many drugs besides clarithromycin may affect the heart rhythm (QT prolongation). Examples include amiodarone, cisapride, disopyramide, dofetilide, pimozide, propafenone, quinidine, sotalol, among others. Therefore, before using this product, report all medications you are currently using to your doctor or pharmacist.Some products need stomach acid so that the body can absorb them properly (such as calcium/iron supplements, erlotinib, azole antifungals including ketoconazole). Lansoprazole decreases stomach acid, so it may change how well these other products work. Before using lansoprazole, consult your doctor or pharmacist about the other medications you take and for advice on how to reduce or avoid these types of interactions.Clarithromycin can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include some benzodiazepines (such as alprazolam, triazolam), carbamazepine, eletriptan, eplerenone, some drugs used to treat erectile dysfunction (such as sildenafil, vardenafil), fentanyl, fesoterodine, ixabepilone, maraviroc, some drugs for organ transplant (such as cyclosporine, tacrolimus, sirolimus), ranolazine, repaglinide, silodosin, some "statin" drugs (such as atorvastatin, lovastatin, simvastatin), temsirolimus, theophylline, tolterodine, among others.Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.This medication may interfere with certain laboratory tests (including urine glucose test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.



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