lamotrigine, Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: lamotrigine

BRAND NAME: Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Lamictal Starter

DRUG CLASS AND MECHANISM: Lamotrigine is an oral drug that is used primarily for treating seizures. It is chemically unrelated to other anti-seizure drugs. The precise mechanism by which lamotrigine exerts its anti-seizure action is not known. The FDA approved lamotrigine in December 1974.

PRESCRIBED FOR: Lamotrigine is used in combination with other anti-seizure drugs for the treatment of partial seizures, tonic-clonic seizures, and seizures of Lennox-Gastaut syndrome. It also is used alone for treating partial seizures in patients 16 years and older when converting from other anti-epileptic drugs. Lamotrigine also is used for preventing mood episodes in individuals 18 years or older with bipolar disorder.

SIDE EFFECTS: The most common side effects of lamotrigine are:

Severe, life-threatening rashes have occurred with lamotrigine. The risk of rash is increased if the dose is increased faster than recommended or if patients also are taking valproic acid. Patients taking lamotrigine should report any rash to a physician immediately.

Medically Reviewed by a Doctor on 12/31/2014

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