LAMIVUDINE/ZIDOVUDINE-ORAL (cont.)
PRECAUTIONS: This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: liver disease. Before using this product, tell your doctor your medical history, including: allergies (especially drug allergies), blood or bone marrow disorders, kidney problems, heart disease, alcoholism, hepatitis B virus infection, major injuries/surgeries/infections. This product is not recommended in children less than 12 years old since the dosage cannot be adjusted for this age group. Lamivudine-containing products should be used with extreme caution in children with pancreatitis. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This product may be excreted into breast milk. Do not breast feed because breast milk can transmit HIV. Consult your doctor or pharmacist for any questions.
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: zalcitabine. If you are currently using any of these medications, tell your doctor or pharmacist before starting lamivudine/zidovudine. Tell your doctor of all nonprescription and prescription medication you may use, especially of: interferons, other drugs that affect the bone marrow (e.g., anticancer drugs, chloramphenicol), abacavir and tenofovir, trimethoprim/sulfamethoxazole, atovaquone, fluconazole, methadone, valproic acid, probenecid, ganciclovir, protease inhibitors (e.g., indinavir, ritonavir). This product contains both zidovudine and lamivudine. Do not take other medicine containing zidovudine or lamivudine unless directed to do so. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include nausea, vomiting, headache, dizziness, drowsiness, and confusion.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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