labetalol, Normodyne, Trandate

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Medical and Pharmacy Editor:

GENERIC NAME: labetalol

BRAND NAMES: Normodyne (Discontinued Brand), Trandate

DRUG CLASS AND MECHANISM: Labetalol is a drug that is used for treating high blood pressure. And is related to carvedilol (Coreg). Nerves from the adrenergic nervous system travel from the spinal cord to arteries where they release norepinephrine. Norepinephrine attaches to adrenergic receptors on arteries and causes the arteries to contract, narrowing the arteries, and increasing blood pressure. Labetalol blocks receptors of the adrenergic nervous system. When labetalol attaches to and blocks the receptors, arteries expand, resulting in a fall in blood pressure. The FDA approved labetalol in August 1984.

PRESCRIBED FOR: Labetalol is used alone or in combination with other drugs to reduce blood pressure.

SIDE EFFECTS AND PRECAUTIONS: The most common side effects of labetalol are:

Medically Reviewed by a Doctor on 12/30/2014



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