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- What is labetalol, and how does it work (mechanism of action)?
- What brand names are available for labetalol?
- Is labetalol available as a generic drug?
- Do I need a prescription for labetalol?
- What are the side effects of labetalol?
- What is the dosage for labetalol?
- Which drugs or supplements interact with labetalol?
- Is labetalol safe to take if I'm pregnant or breastfeeding?
- What else should I know about labetalol?
What is labetalol, and how does it work (mechanism of action)?
Labetalol is a drug that is used for treating high blood pressure. And is related to carvedilol (Coreg). Nerves from the adrenergic nervous system travel from the spinal cord to arteries where they release norepinephrine. Norepinephrine attaches to adrenergic receptors on arteries and causes the arteries to contract, narrowing the arteries, and increasing blood pressure. Labetalol blocks receptors of the adrenergic nervous system. When labetalol attaches to and blocks the receptors, arteries expand, resulting in a fall in blood pressure. The FDA approved labetalol in August 1984.
What brand names are available for labetalol?
None. Normodyne and Trandate are discontinued.
Is labetalol available as a generic drug?
Do I need a prescription for labetalol?
What are the side effects of labetalol?
The most common side effects of labetalol are:
Postural hypotension (a rapid decrease in blood pressure when going from the lying or seated position to the standing position that may cause light-headedness or fainting) occurs rarely. Patients should be observed for this possible side effect within two to four hours of the first labetalol dose and after any changes in dose.
Other important side effects include:
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