In this Article

• What is Klippel-Trènaunay-Weber (KTW) syndrome?
• What is a port-wine stain?
• What is asymmetrical limb hypertrophy?
• Are there other abnormalities in Klippel-Trènaunay-Weber syndrome?
• How is intelligence affected?
• What is the basic defect in Klippel-Trènaunay-Weber syndrome?
• What causes Klippel-Trènaunay-Weber syndrome?
• What is the prognosis (outlook) with Klippel-Trènaunay-Weber syndrome?
• Why is it called Klippel-Trènaunay-Weber syndrome?
• Alternative names for Klippel-Trènaunay-Weber (KTW) syndrome
• Klippel-Trenaunay-Weber Syndrome Glossary
• Klippel-Trenaunay-Weber Syndrome Index

Why is it called Klippel-Trènaunay-Weber syndrome?

In 1900 the French physicians Maurice Klippel and Paul Trènaunay reported the case of a patient with a port-wine stain, asymmetrical overgrowth (hypertrophy) of soft tissue and bone together with hemangiomas of the skin In 1907, the eminent London physician F. Parkes Weber reported three more cases, and noted the varicosities. As is often the case in medicine, those who describe a syndrome are often given credit by having the syndrome named after them. Thus, in 1918 it became know as Klippel-Trènaunay-Weber syndrome.

Alternative names for Klippel-Trènaunay-Weber (KTW) syndrome

Alternative names for Klippel-Trènaunay-Weber (KTW) syndrome include angio-osteohypertrophy syndrome, congenital dysplastic angiectasia, elephantiasis congenita angiomatosa, hemangiectatic hypertrophy, Klippel-Trenaunay- Parkes-Weber syndrome (Parkes was Weber's middle name), Klippel Trenaunay syndrome, KTS, and osteohypertrophic nevus flammeus.

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