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February 10, 2012

Kidney Infection (cont.)

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What are the signs and symptoms of kidney infection?

Some of the common symptoms of kidney infection include:

Signs of kidney infection on exam may include:

  • fever,

  • tenderness on the flanks (costo-vertebral angle tenderness, referring to tenderness upon tapping gently on the mid back on the sides), and

  • clinical evidence of infection in the urinalysis (analysis of urine).

In elderly patients and those with weak immune systems, kidney infection may be more severe with confusion, rapid heart rate, low blood pressure, and dehydration.

How is kidney infection diagnosed?

Kidney infection may be diagnosed by a physician by performing a complete physical examination and taking a detailed medical history. The evaluation includes checking the vital signs (heart rate, blood pressure, temperature, and respiratory rate), assessing for signs of dehydration, and checking for tenderness on the mid and lower back. In young, female patients a pelvic exam may also be necessary to evaluate for pelvic infection (pelvic inflammatory disease or PID). Pregnancy test may also be performed.

Urinalysis test is essential for the diagnosis of kidney infection. The urine sample must be properly collected. The urethra needs to be wiped clean properly before the sample is collected in order to avoid contamination of urine by the bacteria on the skin around the urethra. The initial stream of urine may also be voided in the toilet before the collecting urine in the provided container. This is called the mid-stream, clean-catch urine. After an appropriate amount of urine is collected (about 10 milliliters or cc's) in the container, the remaining urine may also be voided in toilet.

A urinalysis suggestive of an infection in the urine (presence of white blood cells or bacteria in the urine) in general, is highly suggestive and supportive of the diagnosis of kidney infection or urinary tract infection. A urine sample without evidence of urine infection makes kidney infection unlikely and another diagnosis may be considered.

Once white blood cells and other indications of urine infection [such as, leukocyte esterase (produced by white blood cells in urine) or nitrites (produced by bacteria in urine)] are noted on the urinalysis, it is important to determine the amount and the type of bacteria in the urine sample. Generally, a urine sample that has greater than 100,000 bacteria in one cc of urine is considered diagnostic of urinary tract infection. In some clinical settings, counts of less than 100,000 bacteria in one cc of urine may also indicate an infection.


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