ketorolac tromethamine (Acular, Acular LS, Acuvail)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is ketorolac tromethamine-ophthalmic, and how does it work (mechanism of action)?

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) similar to ibuprofen, indomethacin, naproxen, and many others. Ketorolac blocks prostaglandin synthesis. Prostaglandins have many effects in the body including their role in pain and inflammation. In the eye prostaglandin is involved in inflammation, pain, and irritation due to allergies or mechanical injury. Ketorolac provides relief from pain and inflammation in the eyes. The FDA approved ketorolac eye drops in November 1992.

What brand names are available for ketorolac tromethamine-ophthalmic?

Acular, Acular LS, Acuvail

Is ketorolac tromethamine-ophthalmic available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for ketorolac tromethamine-ophthalmic?

Yes

What are the side effects of ketorolac tromethamine-ophthalmic?

Side effects of Ketorolac are:

  • burning and stinging of eyes,
  • corneal edema,
  • inflammation and irritation,
  • eye infection,
  • dryness,
  • visual disturbances, and
  • headache.

Which drugs or supplements interact with ketorolac tromethamine-ophthalmic?

Ketorolac should not be used with other NSAID eye drops due to risks of increased bleeding and delayed healing.

Ketorolac should be used with caution with steroid-containing eye drops due to increased likelihood of infections.

Ketorolac should be used with caution in patients who bleed easily or patients receiving blood thinners.

Medically Reviewed by a Doctor on 9/29/2015
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