ketorolac tromethamine (Acular, Acular LS, Acuvail)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: Ketorolac tromethamine

BRAND NAME: Acular, Acular LS, Acuvail

DRUG CLASS AND MECHANISM: Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) similar to ibuprofen, indomethacin, naproxen, and many others. Ketorolac blocks prostaglandin synthesis. Prostaglandins have many effects in the body including their role in pain and inflammation. In the eye prostaglandin is involved in inflammation, pain, and irritation due to allergies or mechanical injury. Ketorolac provides relief from pain and inflammation in the eyes. The FDA approved ketorolac eye drops in November 1992.

PRESCRIBED FOR: Ketorolac tromethamine eye drops are used for allergic conjunctivitis (pink eye) and for the treatment of post-operative inflammation, pain, burning, and stinging after eye procedures such as cataract surgery and corneal refractory surgery.

Allergic conjunctivitis: Adults and children 2 years and older: Instill 1 drop into affected eye(s) 4 times a day

Post-operative inflammation: Adults and children 2 years and older: Instill 1 drop into operative eye(s) 2 times a day starting 1 day before surgery and continue for 4 weeks when using Acuvail. For Acular, instill 1 drop into operative eye(s) 4 times a day starting 24 hours after procedure and continuing for 2 weeks.

Safe and effective use of Ketorolac is not established for children under 2 years of age.

SIDE EFFECTS: Side effects of Ketorolac are:

  • burning and stinging of eyes,
  • corneal edema,
  • inflammation and irritation,
  • eye infection,
  • dryness,
  • visual disturbances, and
  • headache.
Medically Reviewed by a Doctor on 9/29/2015
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