GENERIC NAME: ketorolac
BRAND NAME: N/A
DISCONTINUED BRAND: Toradol
DRUG CLASS AND MECHANISM: Ketorolac is a member of a class of drugs called nonsteroidal antinflammatory drugs (NSAIDs) that are used for treating inflammation and pain. Other drugs in this class include ibuprofen (Motrin) and naproxen (Naprosyn, Aleve), but ketorolac is more effective than other NSAIDs in reducing pain from both inflammatory and non-inflammatory causes. Ketorolac reduces the production of prostaglandins, chemicals that cells of the immune system make that cause the redness, fever, and pain of inflammation and that also are believed to be important in the production of non-inflammatory pain. It does this by blocking the enzymes that cells use to make prostaglandins (cyclooxygenase 1 and 2). As a result, pain as well as inflammation and its signs and symptoms, redness, swelling, fever, and pain, are reduced. The FDA approved ketorolac in November 1989.
PRESCRIBED FOR: Ketorolac is used for short-term management (up to 5 days) of moderately severe acute pain that otherwise would require narcotics. It should not be used for minor or chronic painful conditions.
SIDE EFFECTS: Common side effects from ketorolac include:
- ringing in the ears,
- abdominal pain,
- heartburn, and
- fluid retention.
Quick GuideChronic Pain: Causes, Solutions and Management
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