Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Ketoprofen may increase the blood levels of
Lithobid) by reducing the excretion of lithium by the kidneys which may lead to lithium toxicity.
Ketoprofen may reduce the blood pressure lowering effects of blood pressure medications. This occurs because prostaglandins play a role in reducing blood pressure.
When NSAIDs are combined with
methotrexate (Rheumatrex, Trexall) or aminoglycosides (for example, gentamicin) the blood levels of methotrexate or aminoglycoside may increase because their elimination is reduced. This may lead to more methotrexate or aminoglycoside side effects.
Individuals taking blood thinners or anticoagulants, for example,
warfarin (Coumadin), should avoid ketoprofen because ketoprofen also thins the blood, and excessive blood thinning may lead to bleeding.