ketoprofen (Discontinued brands: Nexcede, Orudis, Oruvail, Actron) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

People who are allergic to other NSAIDs should not use ketoprofen. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously.

Individuals with asthma are more likely to experience allergic reactions to ketoprofen and other NSAIDs.

Other medical conditions that also have been associated with the use of NSAIDs include:



PREPARATIONS: Capsules (immediate release): 50 and 75 mg; Capsules (extended-release): 100, 150 and 200 mg. Oral Film: 12.5 mg

STORAGE: Ketoprofen should be stored in a sealed container at room temperature, 15 C to 30 C (59 F to 86 F), avoiding moisture and protected from excessive heat.


  • The usual starting dose of ketoprofen is 50 or 75 mg with immediate release capsules every 6 to 8 hours or 200 mg with extended release capsules once daily.
  • The maximum dose is 300 mg daily of immediate release capsules or 200 mg daily of extended release capsules.
  • Ketoprofen should be taken with food in order to avoid stomach upset.
  • Menstrual cramps are treated with 25-50 mg every 6 to 8 hours using immediate release capsules.
  • Rheumatoid or osteoarthritis are treated with 75 mg three times daily or 50 mg four times daily using immediate release capsules or 200 mg daily of extended release capsules.
Medically Reviewed by a Doctor on 5/19/2015

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