ketoprofen None (Note: previous brand names no longer available in the US include Orudis, Oruvail) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Ketoprofen also may cause stomach and intestinal bleeding from ulcers. Sometimes, stomach ulceration and intestinal bleeding occur without any abdominal pain. Black tarry stools (due to blood in the stool), weakness, and dizziness upon standing (orthostatic hypotension) may be the only signs of the bleeding.

People who are allergic to other NSAIDs should not use ketoprofen. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. Individuals with asthma are more likely to experience allergic reactions to ketoprofen and other NSAIDs. Fluid retention, blood clots, heart attacks, hypertension, and heart failure also have been associated with the use of NSAIDs.

Reference: FDA Prescribing Information


Last Editorial Review: 3/26/2009



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