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- What is ketoprofen, and how does it work (mechanism of action)?
- What brand names are available for ketoprofen?
- Is ketoprofen available as a generic drug?
- Do I need a prescription for ketoprofen?
- What are the side effects of ketoprofen?
- What is the dosage for ketoprofen?
- Which drugs or supplements interact with ketoprofen?
- Is ketoprofen safe to take if I'm pregnant or breastfeeding?
- What else should I know about ketoprofen?
What is ketoprofen, and how does it work (mechanism of action)?
Ketoprofen is an oral drug that belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), naproxen (Aleve) and many others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins, chemicals produced by the body that are responsible for pain, fever, and inflammation. Ketoprofen reduces prostaglandins by blocking the enzyme that makes them (cyclooxygenase). As a consequence, inflammation, pain and fever are reduced.
The FDA approved ketoprofen in January 1986.
What brand names are available for ketoprofen?
Is ketoprofen available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for ketoprofen?
What are the side effects of ketoprofen?
The most common side effects from ketoprofen are:
- Ringing in the ears
- Abdominal pain
- Retention of fluid
- Shortness of breath
NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury.
Ketoprofen also may cause stomach and intestinal bleeding from ulcers. Sometimes, stomach ulceration and intestinal bleeding occur without any abdominal pain. Black tarry stools (due to blood in the stool), weakness, and dizziness upon standing (orthostatic hypotension) may be the only signs of the bleeding.
People who are allergic to other NSAIDs should not use ketoprofen. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously.
Individuals with asthma are more likely to experience allergic reactions to ketoprofen and other NSAIDs.
Other medical conditions that also have been associated with the use of NSAIDs include:
- Fluid retention (edema)
- Blood clots
- Heart attacks
- Hypertension (high blood pressure)
- Heart failure
- Hair loss
- Ringing in the ears
Quick GuideOsteoarthritis (OA): Treatment, Symptoms, Diagnosis
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