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KETOPROFEN-RECTAL SUPPOSITORY (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: liver or kidney disease, blood disorders, ulcers, heart disease, alcohol use, high blood pressure, eye disease, rectal bleeding, asthma, nasal polyps, any allergies - especially aspirin/NSAID allergy (e.g., ibuprofen, celecoxib). Use caution when performing tasks requiring alertness. Limit alcohol intake as it may intensify the drowsiness effect of this medication. This medicine may cause stomach bleeding. Daily use of alcohol, especially when combined with this medicine, may increase your risk for stomach bleeding. Check with your doctor or pharmacist for more information. Infrequently, this medication may increase the skin's sensitivity to sunlight. If this happens to you, avoid prolonged sun exposure, wear protective clothing and use a sunscreen. Avoid sunlamps. Caution is advised when this drug is used in the elderly. Tell your doctor if you are pregnant before using this drug. Use of this drug in the last 6 months of pregnancy is not recommended. It is unknown if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you use, especially of: "blood thinners" (e.g., warfarin), other arthritis medication, methotrexate, probenecid, water pills, lithium. Check the labels on all your medicines because they may contain aspirin or aspirin-like NSAIDs (e.g., ibuprofen, naproxen). Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.



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