ketoconazole, Nizoral, Extina, Xolegel, Kuric (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Ketoconazole also may reduce the elimination of some "statins" (for example, simvastatin [Zocor]) leading to an increase in the blood levels of statins and increasing the risk of side effects such as rhabdomyolysis (severe muscle injury).

The risk of abnormal heart beats increases when ketoconazole is combined with amiodarone (Cordarone), bepridil (Vascor), and pimozide (Orap).

PREGNANCY: Ketoconazole has not been adequately studied in pregnant women.

NURSING MOTHERS: A small amount of ketoconazole is secreted in breast milk. Nursing mothers should probably avoid breastfeeding while using ketoconazole.

SIDE EFFECTS: Ketoconazole generally is well tolerated. Ketoconazole can cause rash, itching, nausea, vomiting, abdominal pain, headache, dizziness, fatigue, impotence, and blood count abnormalities. Rarely, ketoconazole has serious allergic reactions (anaphylaxis). Also rarely, ketoconazole has been associated with severe depression, hair loss, and tingling sensations. Liver dysfunction also has been reported. Signs of liver problems include unusual fatigue, loss of appetite, nausea and vomiting, yellowing of the skin (jaundice), dark urine, and pale stools. Development of these symptoms while taking ketoconazole should be reported to a physician.

Reference: FDA Prescribing Information


Last Editorial Review: 4/1/2013



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index

STAY INFORMED

Get the Latest health and medical information delivered direct to your inbox!