Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care. See the entire definition of Acute
Aggressive: In oncology, quickly growing, tending to spread rapidly. As, for example, an aggressive tumor. See the entire definition of Aggressive
Ankle: The ankle joint is complex. It is made up of two joints: the true ankle joint and the subtalar joint: See the entire definition of Ankle
Ankylosing: Undergoing ankylosis (stiffening or fusion of a joint).
Antibody: An immunoglobulin, a specialized immune protein , produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production. See the entire definition of Antibody
Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).
Arthritis in children: Arthritis in children, usually in the form in the form of juvenile arthritis (also called pediatric arthritis ) or rheumatoid arthritis . See the entire definition of Arthritis in children
Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.
Behcet's syndrome: A chronic inflammatory disorder involving the small blood vessels which is characterized by a classic triad of features: ulcers in the mouth, ulcers of the genitalia, and inflammation of the eye (uveitis). The mouth and genital ulcers recur in crops and are painful. The mouth ulcers appear on the inner lining of the mouth, the gums, and tongue. The genital ulcers occur on the scrotum and penis of males and vulva of women and can leave scars. Arthritis is commonplace with Behcet's syndrome, as is involvement of the gastrointestinal system and central nervous system. The cause of Behcet's syndrome is not known. It is more frequent and severe in patients from the Eastern Mediterranean and Asia than those of European descent. Treatment for Behcet's disease is symptomatic and supportive. Medication may be prescribed to reduce inflammation and suppress the immune system. See the entire definition of Behcet's syndrome
Blindness: Loss of useful sight. Blindness can be temporary or permanent. Damage to any portion of the eye, the optic nerve, or the area of the brain responsible for vision can lead to blindness. There are numerous (actually, innumerable) causes of blindness. The current politically correct terms for blindness include visually handicapped and visually challenged. See the entire definition of Blindness
Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively. See the entire definition of Bowel
Childhood: (1) The time for a boy or girl from birth until he or she is an adult. (2) The more circumscribed period of time from infancy to the onset of puberty . See the entire definition of Childhood
Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV. See the entire definition of Diagnosis
Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Eye: The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous. See the entire definition of Eye
Family: 1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.
Feet: The plural of foot, both an anatomic structure and a unit of measure. See the entire definition of Feet
Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.). See the entire definition of Fever
Foot: The end of the leg on which a person normally stands and walks. The foot is an extremely complex anatomic structure made up of 26 bones and 33 joints that must work together with 19 muscles and 107 ligaments to execute highly precise movements. At the same time the foot must be strong to support more than 100,000 pounds of pressure for every mile walked. Even small changes in the foot can unexpectedly undermine its structural integrity and cause pain with every step. See the entire definition of Foot
HLA: The major human histocompatibility system. HLA-typing is done before transplantation to determine the degree of histocompatibility. HLA is an acronym for Human Leukocyte Antigens. See the entire definition of HLA
Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young. See the entire definition of Hospital
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person. See the entire definition of Infection
Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response . See the entire definition of Inflammation
Inflammatory bowel disease: A group of chronic intestinal diseases characterized by inflammation of the bowel -- the large or small intestine. The most common types of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn disease . See the entire definition of Inflammatory bowel disease
Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.
Joint: A joint is the area where two bones are attached for the purpose of motion of body parts. A joint is usually formed of fibrous connective tissue and cartilage. An articulation or an arthrosis is the same as a joint. See the entire definition of Joint
Juvenile: Between infantile and adult as, for example, in juvenile rheumatoid arthritis (onset before age 16 years) and juvenile diabetes (type 1 diabetes).
Juvenile rheumatoid arthritis: See: Arthritis, systemic-onset juvenile rheumatoid.
Knee: The knee is a joint which has three parts. The thigh bone (the femur) meets the large shin bone (the tibia) to form the main knee joint. This joint has an inner (medial) and an outer (lateral) compartment. The kneecap (the patella) joins the femur to form a third joint, called the patellofemoral joint. The patella protects the front of the knee joint. See the entire definition of Knee
Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle. See the entire definition of Leg
Lens: The transparent structure inside the eye that focuses light rays onto the retina (the nerve layer that lines the back of the eye, senses light and creates impulses that go through the optic nerve to the brain). The lens was named after the lentil bean because it resembled it in shape and size. See the entire definition of Lens
Methotrexate : A drug that acts as an antimetabolite and specifically as a folic acid antagonist that inhibits the synthesis of DNA , RNA , and protein . See the entire definition of Methotrexate
Mind: That which thinks, reasons, perceives, wills, and feels. The mind now appears in no way separate from the brain. In neuroscience, there is no duality between the mind and body. They are one.
Necrosis: The death of living cells or tissues. Necrosis can be due, for example, to ischemia (lack of blood flow). From the Greek "nekros" (dead body).
Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health. See the entire definition of Onset
Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure. See the entire definition of Operation
Ophthalmologist: An eye doctor. A physician practicing ophthalmology. An ophthalmologist is an M.D.
Orthopedist: An orthopaedic surgeon, orthopaedics being the branch of surgery broadly concerned with the skeletal system (bones). Orthopedics is how this field of surgery is listed under Physicians & Surgeons in the telephone Yellow Pages in Jacksonville, Florida. This spelling is quite common today. But it is incorrect, erroneous, flat out wrong. Orthopedics would relate the term to the foot because in Latin pedis means foot. Orthopaedics is not merely old-fashioned. It is the correct spelling. What was meant by the term orthopaedics when it was devised goes back to its roots: ortho-, straight + the Greek paes, child = the practice, literally, of straightening the child. If the child had a crooked spine ( scoliosis ), it was the job of the orthopaedist to straighten the child, not just the child's foot. That is why there is no American Academy of Orthopedic Surgery but there is an American Academy of Orthopaedic Surgery. And that is also why orthopaedists look after broken bones. See the entire definition of Orthopedist
Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors. See the entire definition of Pain
Pediatric: Pertaining to children.
Polyarticular: Involving many joints. As opposed to monoarticular (affecting just one joint). From the Latin "articulus," meaning a joint.
Prognosis: 1. The expected course of a disease . 2. The patient's chance of recovery. The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good. See the entire definition of Prognosis
Psoriasis : A reddish, scaly rash often located over the surfaces of the elbows, knees, scalp, and around or in the ears, navel, genitals or buttocks. Psoriasis is an autoimmune disease that is mediated by T lymphocytes. It is also a very common disease, Chronic plaque psoriasis affects approximately 2% of people around the world. About 10-15% of patients with psoriasis develop joint inflammation (inflammatory arthritis ). Treatment options include topical steroid creams, tar soap preparations, and exposure to ultraviolet light. See the entire definition of Psoriasis
Quality of life: An important consideration in medical care, quality of life refers to the patient's ability to enjoy normal life activities. Some medical treatments can seriously impair quality of life without providing appreciable benefit, while others greatly enhance quality of life.
Rash : Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem. See the entire definition of Rash
Reactive arthritis : A chronic form of arthritis featuring the following three conditions: (1) inflamed joints; (2) inflammation of the eyes ( conjunctivitis ); and (3) inflammation of the genital , urinary or gastrointestinal system. See the entire definition of Reactive arthritis
Rheumatoid arthritis : An autoimmune disease which causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Autoimmune diseases occur when the body tissues are mistakenly attacked by its own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with these diseases have antibodies in their blood which target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. While rheumatoid arthritis is a chronic illness (meaning it can last for years) patients may experience long periods without symptoms. See the entire definition of Rheumatoid arthritis
Rheumatoid factor: Rheumatoid factor is an antibody that is measurable in the blood. It is commonly used as a blood test for the diagnosis of rheumatoid arthritis. Rheumatoid factor is present in about 80% of adults (but a much lower proportion of children) with rheumatoid arthritis. It is also present in patients with other connective tissue diseases (such as systemic lupus erythematosus) and in some with infectious diseases (such as infectious hepatitis).
Rheumatology: A subspecialty of internal medicine that involves the non-surgical evaluation and treatment of the rheumatic diseases and conditions. Rheumatic diseases and conditions are characterized by symptoms involving the musculoskeletal system. Many of the rheumatic diseases and conditions feature immune system abnormalities. Therefore, rheumatology also involves the study of the immune system. Classical rheumatology training includes 4 years of medical school, 1 year of internship in internal medicine, 2 years of internal medicine residency, and 2 years of rheumatology fellowship. There is a subspecialty board for rheumatology certification. The American College of Rheumatology is the official organization acting on behalf of the field of rheumatology in the United States.
Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis. See the entire definition of Skin
Spondylitis: Inflammation of one or more of the vertebrae of the spine. Diffuse inflammation of the spine is seen in the disease ankylosing spondylitis . Localized spondylitis is seen with infections of a certain area of the spine, such as in Pott's disease. See the entire definition of Spondylitis
Steroid: A general class of chemical substances that are structurally related to one another and share the same chemical skeleton (a tetracyclic cyclopenta[a]phenanthrene skeleton). See the entire definition of Steroid
Substance: 1. Material with particular features, as a pressor substance. 2. The material that makes up an organ or structure. Also known in medicine as the substantia. 3. A psychoactive drug as, for example, in substance abuse.
Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office. See the entire definition of Surgery
Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease. See the entire definition of Syndrome
Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body. See the entire definition of Systemic
Tendon: The tissue by which a muscle attaches to bone. A tendon is somewhat flexible, but fibrous and tough. When a tendon becomes inflamed, the condition is referred to as tendinitis or tendonitis. Inflamed tendons are at risk for rupture. See the entire definition of Tendon
Therapy: The treatment of disease . See the entire definition of Therapy
Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands). See the entire definition of Tumor
Tumor necrosis factor: A member of a superfamily of proteins , each with 157 amino acids, which induce necrosis (death) of tumor cells and possess a wide range of proinflammatory actions. Tumor necrosis factor is a multifunctional cytokine with effects on lipid metabolism , coagulation , insulin resistance, and the function of endothelial cells lining blood vessels. See the entire definition of Tumor necrosis factor
Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash ." See the entire definition of Viral
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- Complete Blood Count (CBC) - A complete blood count (CBC) measures the concentration of white blood cells, red blood cells, and platelets in the blood and aids in the diagnosis of conditions and diseases such as anemia, malignancies, and immune disorders. Source:MedicineNet
- Antinuclear Antibody Test - Read about antinuclear antibodies (ANAs), unusual antibodies that can bind to certain structures within the nucleus of the cells, are found in patients whose immune system may be predisposed to cause inflammation against their own body tissues. ANAs are indicative of the potential presence of an autoimmune illness. Source:MedicineNet
- Urinalysis - Learn about the urinalysis test. Diseases and conditions such as urinary tract or kidney infection, kidney stones, kidney failure, diabetes, or high blood pressure can be diagnosed or monitored. Source:MedicineNet
- Read 55 more Juvenile Arthritis related articles ...
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