ivermectin (Stromectol)

GENERIC NAME: Ivermectin

BRAND NAME: Stromectol

DRUG CLASS AND MECHANISM: Ivermectin is an anti-parasitic medication. Ivermectin works by binding to invertebrate muscle and nerve cells of parasites, causing paralysis and death of parasites. Ivermectin is active against the non-adult form of Onchocerca volvulus. Ivermectin is also active against intestinal activity of Strongyloides stercoralis. The FDA approved ivermectin in November 1996.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 3 mg

STORAGE: Store ivermectin tablets at temperatures below 30 C (86 F).

PRESCRIBED FOR: Ivermectin is used for intestinal infection caused by Strongyloides stercoralis. Ivermectin is also used for infections caused by non-adult form of Onchocerca volvulus. Off-label use includes treatments for head lice, blepharitis and filariasis.

DOSING:

Dosing is complicated and varies for each disease. Dosing begins with 15 kg weight and varies with weight ranges up to 80 or 85 kg depending on the disease process and based on about 200 mcg ivermectin per kg body weight.

  • Intestinal strongyloidiasis: If weighing more than 85 kg take 200 mcg/kg of ivermectin by mouth as a single dose. If evidence of larvae still present during 3 months following therapy, re-treat with a single dose.
  • Onchocerciasis: If weighing more than 85 kg take 150 mcg/kg of ivermectin by mouth as a single dose. Consider retreatment between 3 to 12 months.
Medically Reviewed by a Doctor on 10/3/2014



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