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- What is itraconazole, and how does it work (mechanism of action)?
- What brand names are available for itraconazole?
- Is itraconazole available as a generic drug?
- Do I need a prescription for itraconazole?
- What are the side effects of itraconazole?
- What is the dosage for itraconazole?
- Which drugs or supplements interact with itraconazole?
- Is itraconazole safe to take if I'm pregnant or breastfeeding?
- What else should I know about itraconazole?
What is itraconazole, and how does it work (mechanism of action)?
Itraconazole is an anti-fungal drug in the same class of drugs as fluconazole (Diflucan), ketoconazole (Nizoral), and miconazole (Micatin, Monistat). It prevents growth of several types of fungi by preventing the fungi from producing the membranes that surround the fungal cells. The FDA approved itraconazole in September 1992.
What brand names are available for itraconazole?
Sporanox, Onmel, Sporanox Pulsepak
Is itraconazole available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for itraconazole?
What are the side effects of itraconazole?
The most common side effects of itraconazole are:
Other important side effects include:
It is important to report any signs or symptoms that may suggest liver dysfunction so that the appropriate laboratory testing can be done. These signs include:
- unusual fatigue,
- poor appetite,
- nausea and/or vomiting,
- yellowing of the eyes (jaundice),
- dark urine or
- pale stool.
Itraconazole should not be used for treatment of onychomycosis in patients with a history of heart failure. It should be discontinued if signs and symptoms of heart failure occur. Symptoms of heart failure include fatigue, edema (fluid retention), shortness of breath, nausea, abdominal pain, and inability to sleep unless sitting upright. Use of calcium channel blockers may increase the risk of heart failure associated with itraconazole (see drug interactions).
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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