SIDE EFFECTS: Stomach upset, diarrhea, headache or dizziness may occur the first few days as your body adjusts to the medication. Other side effects reported include ringing in the ears, fever, sexual dysfunction, depression, drowsiness, trouble sleeping. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor immediately if you develop: severe nausea, yellowing eyes/skin, unusual weakness, dark urine, pale stools, numbness or tingling of the hands/feet. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. Symptoms such as trouble breathing or ankle/foot swelling could also be due to a rare side effect-congestive heart failure; seek immediate medical attention nevertheless. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before using this medication tell your doctor your medical history especially: liver disease (including abnormal liver function tests, or disease caused by other medicines), heart disease (e.g., arrhythmias or congestive heart failure), severe lung disease (e.g., COPD), kidney disease, any allergies. Use caution engaging activities requiring alertness if this medication makes you dizzy or drowsy. Itraconazole should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Do not use this medication to treat fungal nail infections if you are pregnant or could become pregnant during treatment due to the potential for fetal harm. A reliable method of birth control should be used during therapy, and for 2 months after stopping itraconazole therapy. Consult your doctor for more details. Itraconazole is excreted into breast milk. The manufacturer does not recommended breast-feeding while using this drug. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Itraconazole should not be used with the following medications because very serious reactions may occur: certain non-drowsy antihistamines (astemizole, terfenadine), ergot alkaloids (e.g., ergotamine, dihydroergotamine), oral midazolam, certain statin drugs (lovastatin, simvastatin), triazolam. If you are currently taking these medications, tell your doctor or pharmacist before starting intraconazole. If you are currently using repaglinide and gemfibrozil, you should not start taking itraconazole before consulting your doctor. If you are currently using these three medications in combination, tell your doctor or pharmacist immediately. Serious reactions (very low blood sugar) could occur. (Also see Warning section) Before using itraconazole, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of (Also see How To Use section): alprazolam, aripiprazole, atorvastatin, budesoide, buspirone, calcium channel blockers (e.g., verapamil, dihydropyridine type such as nifedipine), certain chemotherapy drugs (e.g., busulfan, docetaxel, vinca alkaloids), cilostazol, oral anti-diabetic drugs (sulfonylureas such as glyburide), drugs for male erectile problems (e.g., sildenafil, tadalafil, vardenafil), drugs which decrease immune system function (e.g., cyclosporine, tacrolimus, sirolimus), eletriptan, eplerenone, halofantrine, certain heart medications (antiarrthymics such as disopyramide, digoxin), HIV protease inhibitors (e.g., indinavir, ritonavir, saquinavir), isoniazid, certain macrolide antibiotics (e.g., erythromycin, clarithromycin), injectable midazolam, nevirapine, other drugs removed by the liver (CYP3A4 substrates), rifamycins (e.g., rifabutin, rifampin), certain anti-seizure drugs (e.g., carbamazepine, phenobarbital, phenytoin), stomach acid reducers (e.g., antacids, cimetidine, omeprazole), tolterodine, trazodone, warfarin. Do not start or stop any medicine without doctor or pharmacist approval.