ISOSORBIDE DINITRATE-SUBLINGUAL (cont.)
PRECAUTIONS: Before using this drug tell your doctor your medical history especially: liver disease, kidney disease, a recent heart attack or stroke, anemia, glaucoma, a recent head injury, a thyroid condition, any drug allergies. Avoid alcohol while taking this medication. The combination can lead to blood pressure being too low. When getting up from a sitting or lying position, do it slowly. Getting up too quickly can cause faintness. Sit down if you feel dizzy. Be careful in hot weather, when exercising or when standing for long periods. This medication can make you prone to fainting in these circumstances. This drug should be used during pregnancy only if clearly needed. It is not known if isosorbide appears in breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur: drugs to treat impotence (e.g., sildenafil, vardenafil, tadalafil). If you are currently using any of these medications, tell your doctor or pharmacist before starting isosorbide dinitrate. Tell your doctor of all medications you may use including prescription and nonprescription drugs, especially: drugs for high blood pressure, certain migraine drugs (ergot alkaloids), high doses of aspirin. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include a persistent, throbbing headache; dizziness; confusion; weakness; sweating; changes in heart rate; changes in vision; flushing; nausea; and vomiting.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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