isoniazid (Nydrazid, Laniazid, INH are all discontinued brands) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Damage to nerves (peripheral neuropathy) may occur with isoniazid and cause numbness and tingling of the hands or feet.

Other rare side effects of the nervous system include:

Pyridoxine (vitamin B6), 10-50 mg/day, decreases the risk of neural side effects.

The rate at which Isoniazid is eliminated by the liver is race-dependent. Thus, 60% of African Americans and whites eliminate Isoniazid slowly compared with only 10%-20% of Asians. Individuals who eliminate Isoniazid slowly are more prone to develop hepatitis and neural side effects with long-term use of Isoniazid.

Other important side effects of Isoniazid include:

Medically Reviewed by a Doctor on 2/11/2015

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