ISONIAZID-INJECTION, Nydrazid
GENERIC NAME: ISONIAZID - INJECTION (eye-so-NYE-uh-zid)
BRAND NAME(S): Nydrazid
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
WARNING: Rarely, this medication has caused severe (sometimes fatal) liver problems (e.g., hepatitis). Liver problems increase with age and with daily use of alcohol. Hepatitis can develop with use of this drug at any time during treatment. Stop using this medication and notify your doctor immediately if you develop unusual fatigue, weakness, loss of appetite, nausea, vomiting, dark urine, yellowing of the eyes or skin, or stomach or abdominal pain. Your doctor may decide to slowly restart isoniazid after these symptoms disappear and lab tests return to normal. People with active (acute) liver problems should not use this medication for preventative treatment until after the liver problems have stopped. Your doctor will monitor your liver function tests at least every month to discuss your progress.
USES: This medication is used to prevent and treat tuberculosis.
HOW TO USE: This medication is injected into a muscle (IM) once daily or use as directed by your doctor. Do not stop using this medication without your doctor's approval. Stopping therapy too early may result in a relapse of the infection. Vitamin B6 (pyridoxine) may be prescribed to prevent numbness and tingling (neuropathy).
SIDE EFFECTS: May cause stomach upset, heartburn, nausea or dizziness. These effects should disappear as your body adjusts to the medication. If these effects persist or worsen, notify your doctor. Notify your doctor if you experience: blurred vision, dark urine, skin rash, yellowing of the eyes or skin, numbness or tingling of the hands or feet. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: kidney or liver problems, diabetes, a history of alcohol use, previous treatment for tuberculosis, allergies (especially drug allergies). Alcohol can reduce the effectiveness of isoniazid and increase side effects. Minimize alcohol consumption. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Isoniazid is excreted into breast milk. Consult your doctor before breast-feeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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