Medications and Drugs
GENERIC NAME: ISONIAZID - INJECTION (eye-so-NYE-uh-zid)
BRAND NAME(S): Nydrazid
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
WARNING: Rarely, this medication has caused severe (sometimes fatal) liver problems (e.g., hepatitis). Liver problems increase with age and with daily use of alcohol. Hepatitis can develop with use of this drug at any time during treatment. Stop using this medication and notify your doctor immediately if you develop unusual fatigue, weakness, loss of appetite, nausea, vomiting, dark urine, yellowing of the eyes or skin, or stomach or abdominal pain. Your doctor may decide to slowly restart isoniazid after these symptoms disappear and lab tests return to normal. People with active (acute) liver problems should not use this medication for preventative treatment until after the liver problems have stopped. Your doctor will monitor your liver function tests at least every month to discuss your progress.
USES: This medication is used to prevent and treat tuberculosis.
HOW TO USE: This medication is injected into a muscle (IM) once daily or use as directed by your doctor. Do not stop using this medication without your doctor's approval. Stopping therapy too early may result in a relapse of the infection. Vitamin B6 (pyridoxine) may be prescribed to prevent numbness and tingling (neuropathy).
SIDE EFFECTS: May cause stomach upset, heartburn, nausea or dizziness. These effects should disappear as your body adjusts to the medication. If these effects persist or worsen, notify your doctor. Notify your doctor if you experience: blurred vision, dark urine, skin rash, yellowing of the eyes or skin, numbness or tingling of the hands or feet. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Drug Interactions - Learn about potential drug interactions you may be exposed to. Drug interactions can occur with prescription drugs, OTC medication, vitamins, herbs, and supplements.
- Liver Blood Tests - Learn about liver blood tests used to detect liver damage disease such as fatty liver, cirrhosis, hepatitis, Tylenol liver damage, and more. This includes measuring the aminotransferases enzymes (AST and ALT levels)
- Tuberculosis - Read about tuberculosis (TB) treatment, diagnosis (skin test), transmission, cause (Mycobacterium) and symptoms. TB infection is a contagious disease that's easily spread.
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