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- What is irbesartan, and how does it work (mechanism of action)?
- What brand names are available for irbesartan?
- Is irbesartan available as a generic drug?
- Do I need a prescription for irbesartan?
- What are the side effects of irbesartan?
- What is the dosage for irbesartan?
- Which drugs or supplements interact with irbesartan?
- Is irbesartan safe to take if I'm pregnant or breastfeeding?
- What else should I know about irbesartan?
What is irbesartan, and how does it work (mechanism of action)?
Irbesartan is an oral medication that is used to treat high blood pressure (hypertension) and diabetic nephropathy or kidney disease. It belongs to a class of drugs called angiotensin receptor blockers (ARBs) which also includes valsartan (Diovan), losartan (Cozaar), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells of blood vessels. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict), which leads to an increase in blood pressure (hypertension ). Irbesartan blocks the angiotensin receptor. By blocking the action of angiotensin, irbesartan dilates blood vessels and reduces blood pressure. The FDA approved irbesartan in September 1997.
What brand names are available for irbesartan?
Is irbesartan available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for irbesartan?
What are the side effects of irbesartan?
The most common side effects of irbesartan are:
- abdominal pain or
- fatigue, and
- reduced blood pressure when rising from a sitting or standing position (orthostatic hypotension).
Other important side effects patients may experience include:
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