ipratropium bromide inhaler, Atrovent, Atrovent HFA

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Understanding COPD

SIDE EFFECTS: The most common side effects associated with ipratropium are:

Ipratropium can cause bronchospasms that can be life-threatening. It can also cause rash, itching, or serious allergic reactions involving closure of the airways.

Because of its anticholinergic effect it may worsen symptoms of benign prostatic hyperplasia and narrow-angle glaucoma.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Nasal Inhaler: 0.03 or 0.06%. Oral Inhaler (aerosol): 0.021 mg/spray

STORAGE: Ipratropium should be kept at room temperature, 15 C-30 C (59 F-86 F). Excessive humidity should be avoided.

DOSING:

  • The recommended dose for allergies is 2 sprays (0.03%) in each nostril 2 or 3 times daily.
  • The dose for treating symptoms of the common cold is 2 sprays (0.06%) in each nostril 3 to 4 times daily.
  • The dose for treating asthma is 8 inhalations every 20 minutes as needed for up to 3 hours.
  • The dose for treating bronchospasms associated with COPD is 2 puffs 4 times daily and additional puffs if needed but not to exceed 12 puffs per day.

DRUG INTERACTIONS: Use with other anticholinergic drugs (for example, atropine) may increase the occurrence of side effects.

PREGNANCY: Studies of ipratropium in animals have not demonstrated negative effects on the fetus. There have been no studies in humans.

NURSING MOTHERS: It is not known if ipratropium is secreted in breast milk. Other medications in the same class of drugs are secreted into breast milk. It is not known whether the small amounts that may appear in the milk are of any consequence to the infant.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 8/4/2015

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