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Intravenous Cholangiogram

Medical Author: Jay W. Marks, M.D.
Medical Editors: Barbara K. Hecht, Ph.D. and Frederick Hecht, M.D.

What is an intravenous cholangiogram (IVC)?

The intravenous cholangiogram or IVC is a radiologic (x-ray) procedure that is used primarily to look at the larger bile ducts within the liver and the bile ducts outside the liver. The procedure can be used to locate gallstones within these bile ducts. IVC also can be used to identify other causes of obstruction to the flow of bile, for example, narrowings (strictures) of the bile ducts and cancers that may impair the normal flow of bile.

How is an intravenous cholangiogram done?

To do an IVC, an iodine-containing dye is injected intravenously into the blood. The dye is then removed from blood by the liver which excretes it into the bile. The iodine is concentrated enough just as it is secreted into bile that it does not need to be further concentrated by the gallbladder in order to outline the bile ducts and any gallstones that may be within them. The gallbladder is not always seen on an IVC since the iodine-containing bile may bypass the gallbladder entirely and empty directly into the small intestine.

What are the risks of an intravenous cholangiogram?

Occasional serious allergic reactions can occur to any iodine-containing dye. These reactions can usually be treated but they rarely may result in the death of the patient.

When is the intravenous cholangiogram useful?

The IVC is not used nearly as much today as it used to be. Its use always was limited because it did not work when there was more than a minimal amount of jaundice, and many of the conditions it was used for caused substantial jaundice. The IVC has been largely replaced by other diagnostic procedures -- by ERCP (endoscopic retrograde cholangiopancreatography), endoscopic ultrasound and, increasingly, by MRI cholangiography, none of which are affected by jaundice.


Last Editorial Review: 10/21/2003




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Intravenous Cholangiogram

What are gallstones?

Gallstones are stones that form in the gall (bile).

  • Bile is a watery liquid made by the cells of the liver that is important for digesting food in the intestine, particularly fat.
  • Liver cells secrete the bile they make into small canals within the liver.
  • The bile flows through the canals and into larger collecting ducts within the liver (the intrahepatic bile ducts).
  • The bile then flows within the intrahepatic bile ducts out of the liver and into the extrahepatic bile ducts-first into the hepatic bile ducts, then into the common hepatic duct, and finally into the common bile duct.

From the common bile duct, there are two different directions that bile can flow.

  • The first direction is on down the common bile duct and into the intestine where the bile mixes with food and promotes digestion of food.
  • The second direction is into the cystic duc...

Read the Gallstones article »



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