POSSIBLE SERIOUS SIDE EFFECTS:
Possible serious side effects include:
- Congestive heart failure
- Autoimmune disorders
- Serious allergic reactions
- Thrombotic microangiopathy (clotting in small blood vessels)
- Injection site skin death
- Liver failure
- Reduced blood cell count
- Drug induced lupus erythematosus
PREPARATIONS: Powder for injection (single use vial): 0.3 mg/vial
DRUG INTERACTIONS: Combining interferon beta-1b with zidovudine (Retrovir) may increase blood levels of zidovudine and the risk of bone marrow suppression.
PREGNANCY AND BREASTFEEDING SAFETY:
- Use of interferon beta-1b has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, interferon beta-1b should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
- It is not known if interferon beta-1b is excreted in breast milk. As many drugs enter breast milk and can potentially cause harm to the nursing infant, interferon beta-1b should be used cautiously in nursing mothers.
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