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- Insulin resistance facts
- What is insulin resistance?
- What causes insulin resistance?
- What is the relationship between insulin resistance and diabetes?
- What medical conditions are associated with insulin resistance?
- Who is at risk for insulin resistance?
- How is insulin resistance diagnosed?
- How is insulin resistance managed?
- Lifestyle changes (diet, weight loss, exercise)
- Medications for insulin resistance?
- What's new in insulin resistance?
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Who is at risk for insulin resistance?
An individual is more likely to have or develop insulin resistance if he or she:
- Is overweight with a body mass index (BMI) more than 25 kg/m2. You can calculate your BMI by taking your weight (in kilograms) and dividing twice by your height (in meters).
- Is a man with a waist more than 40 inches or a woman with a waist more than 35 inches
- Is over 40 years of age
- Is of Latino, African American, Native American or Asian American ancestry
- Has close family members who have type 2 diabetes, high blood pressure, or arteriosclerosis
- Has had gestational diabetes
- Has a history of high blood pressure, high blood triglycerides, low HDL cholesterol, arteriosclerosis (or other components of the metabolic syndrome)
- Has polycystic ovarian syndrome (PCOS)
- Displays acanthosis nigricans
How is insulin resistance diagnosed?
A health care professional can identify individuals likely to have insulin resistance by taking a detailed history, performing a physical examination, and simple laboratory testing based on individual risk factors.
In general practice, the fasting blood glucose and insulin levels are usually adequate to determine whether insulin resistance and/or diabetes is present. The exact insulin level for diagnosis varies by assay (by laboratory). However, a fasting insulin level above the upper quartile in a non-diabetic patient is considered abnormal.