insulin glargine (Lantus) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Type 1 diabetes: For patients 6 years of age and older, patients' total daily insulin requirement must be calculated individually. In the beginning, insulin glargine should be one-third of the requirement, given subcutaneously once daily. The maintenance dose is determined based on individual response, given once daily. Insulin glargine must be used in combination with rapid or short acting insulin.
Type 2 diabetes: Start with 10 units of insulin glargine subcutaneously once daily at the same time every day. The maintenance dose is determined based on individual response.
DRUG INTERACTIONS: There are many drugs that do not directly interfere with insulin glargine, but they may affect glucose breakdown in the body. This necessitates adjustments of insulin glargine doses.
Other drugs that can decrease the blood-sugar-lowering effect of insulin glargine are:
PREGNANCY: Safe and effective use of insulin glargine is not established for pregnant females.
NURSING MOTHERS: It is not known whether insulin glargine enters breast milk; therefore, it should be used with caution in females who are breastfeeding.
REFERENCE: FDA Prescribing Information.
Medically Reviewed by a Doctor on 12/23/2014
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