insulin glargine (Lantus)

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GENERIC NAME: insulin glargine


DRUG CLASS AND MECHANISM: Insulin glargine is a bioengineered (man-made) injectable form of long-acting insulin that is used to regulate sugar (glucose) levels in type 1 and type 2 diabetes. Individuals with type 1 diabetes do not produce insulin on their own; and individuals with type 2 diabetes do not produce enough insulin, or insulin is not as effective due to insulin resistance.

Insulin glargine works the same way as natural human insulin, but it's action lasts longer. It helps diabetic patients regulate glucose or sugar in the body. Insulin glargine works by promoting movement of sugar from blood into body tissues and also stops sugar production in liver. Insulin glargine is man-made insulin that mimics the actions of human insulin.

The FDA approved insulin glargine in April 2000.

PRESCRIBED FOR: Insulin glargine is used to regulate blood sugar in adults and children with type 1 and 2 diabetes.


Common side effects of insulin glargine are:

  • Decreased blood sugar and injection site pain
  • Water retention in the joints and weight gain

Local allergic reactions that may occur at the injection sites are:

Medically Reviewed by a Doctor on 12/23/2014

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