insulin

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Pharmacy Author: Eni Williams, PharmD, PhD
    Eni Williams, PharmD, PhD

    Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Better Blood Sugar Balance

STORAGE: Unopened insulin should be stored between 2 C and 8 C (36 F and 46 F); it should not be placed in a freezer. Insulin vials that are being used can be kept at room temperature for up to a month. All vials should be protected from sunlight and excessive heat. Unused insulin should be thrown away after the expiration date. The vials should never be shaken.

DOSING: The abdomen is the preferred site for insulin injection, but the sites of injection must be rotated in order to prevent erosion of the fat beneath the skin, a condition called lipodystrophy. Dosing is adjusted for each patient. A combination of short acting/rapid acting and intermediate insulin or long acting insulin are typically used.

DRUG INTERACTIONS: Beta blockers (for example, propranolol [Inderal, Indearl LA, Innopran XL], atenolol [Tenormin]) may mask symptoms of low blood glucose and affect how the body uses glucose. Repaglinide (Prandin) increases the risk of low blood glucose while rosiglitazone (Avandia) increases the occurrence of low blood glucose, fluid retention, and heart failure. Thiazide diuretics, steroids, and estrogens reduce the effect of insulin by increasing blood glucose. Levofloxacin (Levaquin) and other fluoroquinolones increase the risk of high or low blood glucose. Monoamine oxidase inhinbitors (for example selegiline), sulfonylureas (for example, glyburide [Diabeta, Glynase]), and yohimbe increase the risk of low blood glucose. Thyroid hormones increase insulin requirements. Insulin alters the chemical properties of pramlintide (Symlin). Therefore, pramlintide and insulin should not be mixed in the same syringe.

Medically Reviewed by a Doctor on 4/14/2015

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