PRECAUTIONS: Tell your doctor if you have had allergic reactions, especially to beef, pork or human insulin and of your medical history especially of: thyroid problems, kidney or liver disease, any current infection. Dosage adjustments may be required when you become ill, are under stress, or when quitting smoking. Consult your doctor if you catch a cold or the flu, become nauseated or if your blood glucose levels are high. Fat deposits can occur if injection site is not rotated. Check your sugar readings before and after exercise. You may need a snack beforehand. Tell your doctor if you are pregnant before using this drug. Insulin is not excreted into breast milk. Nevertheless, consult your doctor before breast-feeding.

DRUG INTERACTIONS: Before you use insulin, tell your doctor of all prescription and nonprescription drugs you are taking especially: beta-blockers (acebutolol, atenolol, betaxolol, esmolol, metoprolol, carteolol, nadolol, penbutolol, pindolol, propranolol, timolol, bisoprolol), fenfluramine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), salicylates (aspirin-like compounds), dexfenfluramine, steroids (e.g., prednisone, hydrocortisone), birth control pills, sulfa antibiotics, water pills, ACE inhibitors, octreotide, isoniazid, niacin, estrogens, cold and allergy drugs, drugs that contain alcohol or sugar. Other medications can affect the action of insulin and can alter the results of urine tests for sugar or ketones. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include unconsciousness, seizures, muscle weakness, slow or shallow breathing, headache, vomiting, fever, diarrhea, shakiness, nervousness, fast heartbeat, hunger, or sweating.

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