influenza vaccine live intranasal; FluMist, FluMist Quadrivalent (cont.)

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PREPARATIONS: Intranasal Spray: prefilled single use intranasal spray, 0.2 ml

STORAGE: FluMist should be stored refrigerated between 2 C to 8 C (35 F to 46 F).

PRESCRIBED FOR: FluMist is used for preventing influenza virus infections (flu) in individuals 2 to 49 years of age.

DOSING: Children 2 to 8 years of age who have not previously received FluMist should be given 2 doses of 0.2 ml at least one month apart. Children 2 to 8 years of age, who previously received FluMist and adults 9 to 49 years of age, should be given 1 dose (0.2 ml) of FluMist each season. FluMist is administered by inhaling through the nose while standing or sitting in an upright position. FluMist is not administered by injection.

Since FluMist contains viruses that are likely to cause the flu in the upcoming season, FluMist developed for previous seasons will not be effective and should not be used.

DRUG INTERACTIONS: Children 5 to 17 years of age who are receiving aspirin therapy should not be given FluMist because of the association between aspirin, influenza infection, and Reye's syndrome, a serious disease of the liver.

Use of FluMist together with antiviral drugs that are active against the influenza virus has not been evaluated. Since there is a potential for antiviral drugs to reduce the effectiveness of FluMist (by preventing infection with the weakened viruses in FluMist), antiviral drugs should not be administered until 2 weeks after FluMist therapy, and FluMist should not be administered until 48 hours after antiviral therapy is discontinued.

Administering FluMist with inactivated virus vaccines was not evaluated in FluMist clinical trials, and combining FluMist with other intranasal products has not been evaluated. FluMist did not interfere with, and was not affected by measles, mumps, rubella, or varicella live vaccines.

PREGNANCY: FluMist should not be given to pregnant women.

NURSING MOTHERS: Use of FluMist during breastfeeding has not been adequately evaluated, and it is not known whether FluMist is excreted in breast milk.

Medically Reviewed by a Doctor on 1/27/2014

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