indomethacin, Indocin, Indocin-SR (Discontinued Brand in U.S.)

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Medical and Pharmacy Editor:

GENERIC NAME: indomethacin

BRAND NAME: Indocin, Indocin-SR (Discontinued Brand in U.S.)

DRUG CLASS AND MECHANISM: Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that reduces fever, pain and inflammation. It is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve). Indomethacin works by reducing the production of prostaglandins. Prostaglandins are chemicals that the body produces and which cause the fever and pain that are associated with inflammation. Indomethacin blocks the enzymes that make prostaglandins (cyclooxygenase 1 and 2) and thereby reduces the levels of prostaglandins. As a result, fever, pain and inflammation are reduced. Indomethacin is available in an extended release form. The FDA first approved indomethacin in January 1965.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Capsules: 25 and 50 mg
  • Capsules, extended release: 75 mg
  • Suspension: 25 mg/ml
  • Suppositories: 50 mg.
  • Injection (powder): 1 mg

STORAGE: Capsules should be kept at room temperature, 15 C to 30 C (59 F to 86 F). Oral suspension and suppositories should be kept below 30 C (86 F). The oral suspension should not be frozen.

Medically Reviewed by a Doctor on 12/5/2013



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