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Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Some medications are changed and broken down by the liver. Indole-3-carbinol might increase how quickly the liver breaks down some medications. Taking indole-3-carbinol along with some medications that are changed by the liver can decrease the effectiveness of some medications. Before taking indole-3-carbinol, talk to your healthcare provider if you take any medications that are changed by the liver.
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