indapamide, Lozol (Discontinued) (cont.)

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Medical and Pharmacy Editor:

Other important side effects include:

PREGNANCY AND BREASTFEEDING SAFETY: The use of indapamide in pregnancy has not been well studied. Physicians may elect to use it if its benefits are judged to outweigh its potential risks. The use of indapamide in nursing mothers has not been studied.

PREPARATIONS: Tablets: 1.25 and 2.5 mg.

DRUG INTERACTIONS: Like other diuretics, indapamide can cause hypokalemia (low potassium) and hypomagnesemia (low magnesium). These changes can increase the risk of digoxin (Lanoxin) toxicity, possibly resulting in fatal abnormal heart rhythms. Use of amiodarone (Cordarone) and indapamide also can lead to cardiac arrhythmias. The ability of the kidney to eliminate lithium (Lithobid, Eskalith) is decreased in patients receiving diuretics, including indapamide. The use of these two drugs together could result in lithium toxicity.

Medically Reviewed by a Doctor on 1/14/2016


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