indapamide, Lozol (Discontinued)

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GENERIC NAME: indapamide

BRAND NAME: Lozol (discontinued brand)

DRUG CLASS AND MECHANISM: Indapamide is a diuretic (water pill) that is used primarily for the treatment of high blood pressure. It works by preventing the kidney from reabsorbing (retaining in the body) salt and water that is destined to be eliminated in the urine. This results in increased urine output (diuresis). Indapamide also is thought to reduce the salt in the smooth muscle of the walls of blood vessels. (The salt ultimately is eliminated in the urine.) The loss of salt from the muscle causes the muscle to relax, and the relaxation of the vessels results in reduced blood pressure. Indapamide was approved by the FDA in 1983.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablets: 1.25 and 2.5 mg.

STORAGE: Indapamide should be stored between 15-30 C (59-86 F).

PRESCRIBED FOR: Indapamide is used to treat hypertension (high blood pressure) and accumulation of excess fluid (edema), which may result from congestive heart failure.

DOSING: Indapamide is taken as a single daily dose, generally in the morning before breakfast. The recommended dose range is 1.25 to 5 mg once daily. It can be taken with or without food. Antacids have no effect on the activity of Indapamide.




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